Alex Speier reports that the arbitration hearing between the Red Sox ($12.65 million) and David Ortiz ($16 million) is scheduled for Monday. The two sides could, of course, settle before that time. The Red Sox have not gone to arbitration since 2002, when then-GM Dan Duquette could not come to an agreement with pitcher Rolando Arrojo.Scott Atchison, who turns 36 on March 29, cleared waivers and was assigned to Pawtucket.Evan Drellich presents an organization overview with a peek at MLB's ranking of the Red Sox's top prospects:The first four names - and five of the first seven - on MLB.com's…
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Ortiz Arbitration Hearing Set For Monday
the joy of sox8 Feb 2012 | 7:32 pm -
The Learning Network Blog: How Do Male and Female Roles Differ in Your Family?
NYT > Education9 Feb 2012 | 4:17 amTell us about the gender roles in your house. Who would you say does most of the "parenting," whether that means helping with homework, cooking meals, attending school functions or just being home most often--and whether it's done by a mother or father, or by a sibling, grandparent or someone else? -
We need to stop arguing over which factory-age solutions we should try
Dangerously Irrelevant6 Feb 2012 | 4:13 amTrace Pickering recently sent me a slide deck that's definitely worth viewing. Trace is a wonderful systems thinker. His slides do a nice job of describing historical shifts in American society and the concurrent changes that were necessary in American education. As he notes about our current era, We seem to be stuck … arguing over which factory-age solutions we should try without fully understanding the implications of the context we are in and the new functions we need education to perform. Trace's slides are embedded below. He's kindly made them available with a Creative Commons license. -
Ideas I'd Like My Future Principal to Consider: The Schedule
The Fischbowl5 Feb 2012 | 9:59 amWe have a problem with time. Specifically, the way we allocate it in schools. As Chris Lehmann points out:Our schools are structurally dysfunctional places which, therefore, makes teaching and learning much harder than it needs to be, so that teachers -- and students -- have to succeed despite the system, rather than because of it.As long as high school students have to travel to eight different classes where eight different teachers talk about grading / standards / learning in eight different ways, students will spend far too much trying to figure out the adults instead of figuring out the… -
The Week in Tweets for 2012-02-06
Bud the Teacher6 Feb 2012 | 5:15 amReviewing the writing we did together at #educon Interesting how people define "research" and "impact." Or don't. http://t.co/wALcdmaQ # Also looking forward to @jonbecker's coordination of some teacher research as an outcome of the session. Important. # @courosa @msstewart We're about to enable the Google Apps for Ed addon for Sliderocket – looks good. in reply to courosa # @msstewart @courosa @nwhyluckysgirl A couple of our teachers said the other version was more fully featured – but I don't have specifics. in reply to msstewart #…
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the joy of sox
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Ortiz Arbitration Hearing Set For Monday
8 Feb 2012 | 7:32 pmAlex Speier reports that the arbitration hearing between the Red Sox ($12.65 million) and David Ortiz ($16 million) is scheduled for Monday. The two sides could, of course, settle before that time. The Red Sox have not gone to arbitration since 2002, when then-GM Dan Duquette could not come to an agreement with pitcher Rolando Arrojo.Scott Atchison, who turns 36 on March 29, cleared waivers and was assigned to Pawtucket.Evan Drellich presents an organization overview with a peek at MLB's ranking of the Red Sox's top prospects:The first four names - and five of the first seven - on MLB.com's… -
What Do The Yankees Smell Like?
7 Feb 2012 | 3:33 pmWanna smell like the Yankees?On February 21, you will have your chance. That's the day the team will introduce two "official fragrances" called, creatively enough: "New York Yankees" and "New York Yankees for Her".(Note the overt sexism where what should be called "New York Yankees For Him" is simply "New York Yankees".)Mike Silva, New York Baseball Digest: "Yes, every team has non-baseball related products. You have checkers, chess, teddy bears, etc. with the team logo. None of the 29 other teams believe they are bigger than the game where they create a fragrance and have a bourgeois… -
Happy Birthday, Babe!
6 Feb 2012 | 8:17 amBabe Ruth - known as the Colossus when he played with the Red Sox - was born 117 years ago today. -
Nick Cafardo Still Refuses To Do Even Minimal Work
5 Feb 2012 | 1:39 pmFrom today's Sunday Notes column:Boras sees openings for [Johnny] Damon. The Yankees could use a DH type. The Orioles signed Wilson Betemit, but please . . . Betemit, who hit eight homers with two teams, over Damon, who hit 16 homers for Tampa Bay?So Nick's entire argument for Damon's DH potential is that he hit twice as many home runs last year as (please) Betemit. Unfortunately for his readers, Nick did not take 30 seconds out of his entire week to find some extremely basic stats:Damon BetemitHome Runs 16 8Plate Appearances 647 359PA/HR 40.4 44.9Slugging Percentage .418 .452And even though… -
Matsuzaka Airs It Out In Second Session
5 Feb 2012 | 9:58 amYakyubaka.com:Daisuke Matsuzaka tossed his second bullpen session on February 3 (February 4 in Japan) -- twenty pitches to a catcher that squatted in front of the home plate."While I threw at about 70% last time, this time I tried to throw as hard as I could. I am glad that I was able to throw at close to 90%," said Matsuzaka. "A part of me is still holding back. I want to continue examining my mechanics moving forward."Alfredo Aceves and the Red Sox avoided arbitration by agreeing on a $1.2 million deal for this season (with an additional $100,000 in potential incentives). The team's only…
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NYT > Education
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The Learning Network Blog: How Do Male and Female Roles Differ in Your Family?
9 Feb 2012 | 4:17 amTell us about the gender roles in your house. Who would you say does most of the "parenting," whether that means helping with homework, cooking meals, attending school functions or just being home most often--and whether it's done by a mother or father, or by a sibling, grandparent or someone else? -
SchoolBook: Something to Say? We've Made It Simpler
9 Feb 2012 | 4:10 amConversation — along with news and data — is one of the three key pillars of SchoolBook, and we wanted to do everything we could to make it flourish. So we have added open-ended comment threads on posts to make it easier for you to weigh in on all the issues, ideas, news and opinions that touched, angered, inspired or entertained you. -
The Choice Blog: Dean Wormer's Guide to Some Fantastic Colleges
9 Feb 2012 | 3:00 amCould the best college for you be one that doesn't exist? -
The Learning Network Blog: 6 Q's About the News | Proposition 8 Struck Down
9 Feb 2012 | 1:44 amWhat clause in the Constitution was the basis for the decision? -
The Learning Network Blog: Test Yourself | Feb. 9, 2012
9 Feb 2012 | 1:03 amCan you choose the sentence that is punctuated correctly?
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Dangerously Irrelevant
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We need to stop arguing over which factory-age solutions we should try
6 Feb 2012 | 4:13 amTrace Pickering recently sent me a slide deck that's definitely worth viewing. Trace is a wonderful systems thinker. His slides do a nice job of describing historical shifts in American society and the concurrent changes that were necessary in American education. As he notes about our current era, We seem to be stuck … arguing over which factory-age solutions we should try without fully understanding the implications of the context we are in and the new functions we need education to perform. Trace's slides are embedded below. He's kindly made them available with a Creative Commons license. -
Digital Learning Day: The aftermath
2 Feb 2012 | 5:51 amWell, yesterday was Digital Learning Day. By all accounts, it was a busy day across the country. Lots of conversation and high-profile events and demonstrations of students doing cool stuff with technology... Should every school day be Digital Learning Day? Nope. We still need down time from these electronic and virtual spaces of ours, times when we experience the joy of human connection, nature, solitude, reflection (and all of those other things that people say I should be experiencing!). But, nonetheless, we definitely need 'more digital, more often' in most of our primarily-analog… -
Announcing our new School Technology Leadership courses: Get a graduate certificate, Master’s, or Ph.D.
1 Feb 2012 | 10:48 amShort version We're relaunching our online School Technology Leadership courses and programs today! Woo hoo! (This is all pending final approval by Faculty Senate) Long version It's Digital Learning Day here in the U.S. As I said in my guest post for the event: We ... need school leaders who can begin envisioning the implications of these [new technology-suffused, globally-interconnected] environmental characteristics for learning, teaching, and schooling. We need administrators who can design and operationalize our learning environments to reflect these new affordances. I also said: If… -
Keeping Students Engaged in a 1:1 Project-Based Classroom [guest post]
29 Jan 2012 | 3:55 pmImage approved for copy by Creative Commons. Source: http://bit.ly/vYUkXB When laptops first arrived in my classroom, I worried about classroom management. How could I create an environment where students used their computers as tools rather than toys? I was worried for nothing. The following are suggestions for keeping students engaged in a project and accountable for their time with computers: Students make a plan. Students are most tempted to open widgets, games, and social chats when they are faced with a blank screen and have no plan. Much of the time, students think they have… -
Flawed, ideological, non-peer-reviewed studies should not rebut decades of anti-retention research
29 Jan 2012 | 8:41 amIowa Governor Terry Branstad's recent remarks about retaining 3rd graders confirm both the potential positives and the many negatives of in-grade retention in elementary school. First, the potential positives: in-grade retention sometimes leads to short-term (1 to 2 years out) - and maybe even mid-term (3 to 5 years out) - academic gains. The peer-reviewed research shows that these test score gains occasionally occur when you force kids to repeat 3rd grade, partly because 4th grade test scores look better when low-achievers have been removed from the grade cohort and partly because retained…
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The Fischbowl
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Ideas I'd Like My Future Principal to Consider: The Schedule
5 Feb 2012 | 9:59 amWe have a problem with time. Specifically, the way we allocate it in schools. As Chris Lehmann points out:Our schools are structurally dysfunctional places which, therefore, makes teaching and learning much harder than it needs to be, so that teachers -- and students -- have to succeed despite the system, rather than because of it.As long as high school students have to travel to eight different classes where eight different teachers talk about grading / standards / learning in eight different ways, students will spend far too much trying to figure out the adults instead of figuring out the… -
Tools I'd Like My Future Principal To Consider: Twitter
1 Feb 2012 | 2:50 pmFrom the article Meet Your New PD Tool in Scholastic Administrator magazine:"I really think anybody who doesn't spend a little time building a personal network is doing themselves and their school a disservice. If we're not modeling this stuff for our teachers and students, then I don't think we're doing our… -
Discussing Little Brother with Cory Doctorow: Take Two
30 Jan 2012 | 8:01 pmAnne Smith and Maura Moritz's students will once again be discussing Little Brother with author and blogger Cory Doctorow. A different set of students had this opportunity two years ago and it was a great experience (see that post for more details on the bigger picture of the unit), so we're really looking forward to this.If you're available at 8:30 am Mountain Time on Tuesday, January 31st, feel free to join us in the live stream or the live blog. Mr. Doctorow will be responding to our students' questions live via Skype from London (the stream will be a not-so-great quality webcam-based… -
Crowdsource My Basement Design
29 Jan 2012 | 12:06 pmOkay, so this is kind of a silly post that I actually don't believe will generate anything, but I thought it might be fun anyway. We're about to finish our basement and I am not a very visual person, so trying to picture what it might look like is difficult for me. I'm sure we'll get lots of help with that from the contractor and most likely will go with one of the designs they come up with, but I thought it might be fun to see if I could tap into the wisdom of my small crowd.We currently have a "full," unfinished walkout basement with a wood floor (with some crawl space underneath). We've… -
Quotes I'd Like My Future Principal to Ponder: Participatory Media Education and Civic Education Are Inextricable
23 Jan 2012 | 5:37 pmFrom the article titled "Head of State" in the print edition (subscription required, although if you are in a school you most likely have access to it through one of your library subscription services) in the November 7th, 2011 issue of Time magazine:Whereas US Envoys once filed secret cables to Washington late at night, Clinton has pushed her ambassadors to expand the use of Twitter and Facebook - State now has 192 Twitter feeds and 288 Facebook accounts - and her daughter Chelsea calls her TechnoMom. "We are in the age of participation," Clinton said at her husband's charity even in New…
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Bud the Teacher
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The Week in Tweets for 2012-02-06
6 Feb 2012 | 5:15 amReviewing the writing we did together at #educon Interesting how people define "research" and "impact." Or don't. http://t.co/wALcdmaQ # Also looking forward to @jonbecker's coordination of some teacher research as an outcome of the session. Important. # @courosa @msstewart We're about to enable the Google Apps for Ed addon for Sliderocket – looks good. in reply to courosa # @msstewart @courosa @nwhyluckysgirl A couple of our teachers said the other version was more fully featured – but I don't have specifics. in reply to msstewart #… -
The Week in Tweets for 2012-01-30
30 Jan 2012 | 5:15 am@nawalnader That's backward. Funding after the student's done? How does a school start under that model? in reply to nawalnader # Reviewing district copyright policy. http://t.co/7z0v7Chc # Spent the day in training. Reaffirmed that working with video is hard. # Opportunity to build a blended learning school. Interesting. http://t.co/jtlTF4LT # @MrMacnology I love Hazel. Don't use it as much as I could but it's great. in reply to MrMacnology # @msstewart @jonbecker No problem. I got this. Just point me towards the audience. in reply to msstewart # First day in a couple of… -
#Educon 2.4: Talking Teacher Research
28 Jan 2012 | 5:40 amLater today, I’m honored to be joining my friends and colleagues Jon Becker and Meredith Stewart as we facilitate a session at Educon 2.4 on teacher research and professional development. Specifically, on how we can be critical, in a good way, in our choice and craft of professional development. Here’s the session description: # #edchat #RSCON3 #140edu #TEDx______ #edcamp____ # Many of the educators who participate(d) in the events listed above and others like them report that the events are/were perfectly wonderful; amazing even. Apparently, this social media-aided PD is more… -
Schooling That Isn’t School-y
27 Jan 2012 | 10:46 pmI sat in on a meeting today of the organizers of our school district’s Innovation Academy, a summer STEM enrichment program that’s a partnership between the district and IBM.1 # The DLC will be embedding a teacher research group within the Innovation Academy and its planning in order to see if the work they’re doing, and that students and district staff are enthusiastic about, has something to teach us about how we can make positive change in the classroom. # During the meeting, two statements really caught my ear and got me thinking about the work ahead. # The first was a… -
#DMLBadges for Teachers: We Missed Here, Too
24 Jan 2012 | 2:47 pmJustin Reich and I recently submitted a proposal to the DML Teacher Mastery and Feedback Badges Competition. And, like my recent submission to the DML Conference, it wasn’t accepted. # But that’s cool. I was curious about the process and I learned a bunch about the problems and opportunities of badges and badging. In case you were curious, below is the full text of the application. You can read the winning Stage 1 proposals on the DML Competition Website. # Teacher inquiry has long been recognized as a valuable way for teachers and students to critically examine their…
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danah boyd | apophenia
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World Economic Forum: More than Meets the Eye
29 Jan 2012 | 7:16 pmI spent the last week at the World Economic Forum in Davos, Switzerland. When my friends (y’all) learned I was going, some were supportive while others were horrified. A few called me an outright traitor. Given how much mythology there is around this event, I want to take a moment and briefly share my own experience there. If you read news articles about WEF, you get the impression that it’s a high stakes event where many of the world leaders gather to discuss governance and finance. (Journalists especially love to highlight when said leaders snicker or snark at one another.)… -
How Parents Normalized Teen Password Sharing
23 Jan 2012 | 1:24 pmIn 2005, I started asking teenagers about their password habits. My original set of questions focused on teens’ attitudes about giving their password to their parents, but I quickly became enamored with teens’ stories of sharing passwords with friends and significant others. So I was ecstatic when Pew Internet & American Life Project decided to survey teens about their password sharing habits. Pew found that one third of online 12-17 year olds share their password with a friend or significant other and that almost half of those 14-17 do. I love when data gets reinforced. Last… -
We need to talk about piracy (but we must stop SOPA first)
17 Jan 2012 | 6:51 amMuch to my happiness, the internets are in a frenzy about the “Stop Online Piracy Act” (aka SOPA). Congress is currently in recess, but the House announced a hearing on the potential impact to the Domain Name Service on January 18 and everyone expects the Senate to begin discussing a similar bill “PROTECT IP Act” when they return to DC on January 24. There’s a lot to these bills – and the surrounding furor – and I’m not going to go into it, but I recommend reading the actual bill and Open Congress info, the Wikipedia article, EFF’s blog,… -
Nancy Baym, Kate Crawford, Mary L. Gray to Join Microsoft Research
12 Jan 2012 | 7:19 am::bounce:: I am *ecstatic* to announce that Nancy Baym, Kate Crawford, and Mary L. Gray are all joining Microsoft Research New England in Cambridge, MA. See Jennifer Chayes’ announcement. ::bounce:: Three years ago (this week), I joined Microsoft Research to help integrate social scientists and computer scientists. I have known about and admired MSR since my undergraduate days when I was studying computer science. From the perspective of a researcher, it seemed like heaven-on-earth. As I slowly shifted disciplines, I was saddened to think that I had moved myself away from MSR so I was… -
I am Generation Flux
10 Jan 2012 | 11:05 amI love talking with smart journalists. When they’re good at what they do, journalists can really prompt me to think deeply (and differently) about issues. Nothing makes me happier than coming out of a discussion with a journalist with my brain on fire. My conversation with Bob Safian from Fast Company did precisely that. I left that chat high as a kite with all my synapses buzzing. The funny thing? I didn’t know why he was asking all of those interesting questions. Then, a few weeks later, I was asked to do a photoshoot. And that too ended up being way way way too much fun.
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Curious Cat Science and Engineering Blog » K-12
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Kindergarten Students Pedel Their Own Bus to School
7 Feb 2012 | 11:31 pmDutch kindergarden students pedaling their bus to school Dutch Kids Pedal Their Own Bus To School The Dutch are bicycle fanatics. Almost half of daily travel in the Netherlands is by bicycle, while the country’s bike fleet comfortably outnumbers its 16 million people. Devotees of the national obsession have taken the next logical step by launching what is likely the first bicycle school bus. Built by Tolkamp Metaalspecials, and sold by the De Cafe Racer company, the bicycle school bus (BCO in Dutch) is powered entirely by children and the one adult driver (although there is an electric… -
10 Year Old’s Molecule Design Becomes the Topic of a Scientific Paper
3 Feb 2012 | 3:57 am10-Year-Old Helps Professor With Theoretical Chemistry by Marimar White-Espin [10-year-old Clara] Lazen’s teacher, Kenneth Boehr, introduced Border Star Montessori School’s 5th grade class to the periodic table, molecules and chemical bonds. Lazen found the topic interesting and Boehr gave her the tools she needed to explore the subject. Equipped with a molecule-building kit, Lazen experimented with the colored wooden balls by creating existing molecules and some of her own. Lazen approached Boehr and asked if the molecule she created using the kit was real. Unsure of the answer, Boehr… -
Journal of Emerging Investigators Will Publish Middle and High School Student Research Papers
16 Jan 2012 | 1:57 amThe Journal of Emerging Investigators is a new journal for publishing research paper and reviews of research papers by middle school and high school students from any country. The Journal of Emerging Investigators strives to provide students with as much access to original scientific writing as possible. With this in mind, all submissions are covered by an attribution non-commercial, no derivative license. This means that anyone is free to share, copy and distribute an unaltered article for non-commercial purposes. Graduate students with substantial research experience will review the… -
20th Annual US First Robotics Competition
8 Jan 2012 | 5:20 pmIf you have a child, niece, nephew, grandchild… who you haven’t been able to convince about the wonders of science maybe the starts on this promo (Justin Timberlake, Snoop Dogg, Justin Bieber…) can help convince them. If you want to convince your grandparents science is cool, then maybe they will like the cameos by Steven Tyler and Bono This is an effort being pushed by will.i.am (Black Eyed Peas) and Dean Kamen (US First Founder) to promote science and engineering. Since most politicians don’t seem interested in promoting and supporting science anymore maybe musicians… -
YouTube SpaceLab Experiment Competition
24 Nov 2011 | 2:01 amYouTube SpaceLab is an open competition inviting 14 – 18 year olds (anywhere in the world) to create an idea for a science experiment in space. You don’t have to actually do the experiment, you just have to record yourself explaining it. Entries must have be submitted on YouTube by 07:59 GMT on December 8th. The winning experiments will be conducted on the International Space Station (ISS) and beamed live on YouTube for the whole planet to see. Winners get the choice to either watch the rocket blast off with your idea on it in Japan or take a specially tailored astronaut training…
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Science teacher
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Siemen's STEM Institute: A Luddite Wants In
6 Feb 2012 | 5:36 pmI would like very much to go to the Siemen's STEM Institute this summer, though after today, I'm not sure they'd welcome me in their midst. I've spent hours wrestling with a Flip camera, MS Movie Maker, and and apparent conflict between the chip set in my laptop and the rest of the world (a chip with a chip on its shoulder), and may be disqualified for my inability to produce a simple two minute video broadcasting my Luddite qualities.I have a fine 1956 Futura typewriter sitting in my room, ready to type up a cogent argument for my presence. Which may just highlight the… -
The Dayton Street shuffle
4 Feb 2012 | 5:41 amThe superintendent of the Newark Public Schools system announced that the city state will close down seven schools; the fate of the students and staff has not yet been publicly announced. Ms. Anderson's attempt to go into specifics ended with her walking off the stage.I've spent some time in one of the schools--Dayton Street. I was involved with "The Rainbow Room," a school-based health clinic named by the students.Many of the kids come from a local housing project, where I once made house calls. It's a gritty neighborhood in a tough town adjacent to a beautiful park, and (shhhh...it's a… -
Elementary science lesson
2 Feb 2012 | 6:01 pmI love my Newton's cradle, and various versions have amused me for decades now. Harrod's popularized them as desktop toys way back when, but not because they're scientifical.They're just plain fun.They're also as obvious as the nose on a polar bear's face. Five balls banging against each other, in unexpected yet predictable and repeatable ways.Just don't use the words inertia or force, or, Zeus forbid, Newton's Third Law.Give a pair of children a Newton's cradle. Hold up a ball (or let one of them do it), and let it fall.Hold up two, and do the same.Have the children take turns… -
Imbolc
1 Feb 2012 | 6:33 pmAn Cailleach Bhearra wandered around back in the 10th century in western Ireland, eating "seaweed, salmon, and wild garlic" (my kind of woman), looking for firewood.If the day was bright and sunny, beware--she had gathered plenty of wood and was set for many cold days ahead. If the day was gray, she didn't bother, and she will make the days warm up again. Sound familiar?Imbolc again.The daffodils have broken through the earth. My words shrink as the sunlight grows.Groundhog Day has always been a favorite of mine.***We are trapped by words.This week my lambs are being tested. They sit silently… -
New Jersey versus General Ripper
31 Jan 2012 | 6:15 pmI realize that this is going to push me on wrong side of the angels, but really, folks, take a good hard look at the wheelsbefore jumping on any bandwagon. Even a stopped clock is right twice a year.Yep, a reprint, but New Jersey's under attack by do-gooding, mean-welling folk who need to find a new hobby, A foreign substance is introduced into our precious bodily fluids without the knowledge of the individual. Certainly without any choice. That's the way your hard-core Commie works.General Jack D. RipperDr. Strangelove or: How I Learned to Stop Worrying and Love the BombAh, March…
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EurekAlert! - Education
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Playing school sports affects youths' smoking
7 Feb 2012 | 9:00 pm(Society for Research in Child Development) A new study of middle schoolers and their social networks has found that teammates' smoking plays a big role in youths' decisions about smoking, but adolescents who take part in a lot of sports smoke less. The study looked at 1,260 ethnically diverse, urban, middle-class sixth through eighth graders and used a new social network method designed by the researchers to examine how participation in sports with teammates who smoked affected adolescents' smoking behavior. -
New study: Adolescents suffering from depression more likely to be bullied
7 Feb 2012 | 9:00 pm(Arizona State University) A new study provides evidence that adolescents who suffer from depression are more likely to develop difficulty in peer relationships including being bullied at school. It's often assumed that being bullied leads to psychological problems, such as depression, but the study doesn't support this line of thought. -
Depression forecasts difficulties with peers in middle childhood
7 Feb 2012 | 9:00 pm(Society for Research in Child Development) A longitudinal study of children in the middle years of childhood has found that depression forecasts problems in peer relationships, including being victimized by peers and problems being accepted by peers. For the study, researchers looked at 480 youths from fourth through sixth grades and used child, classmate, parent, and teacher surveys to gather data. -
Study examines role of bilingualism in children's development
7 Feb 2012 | 9:00 pm(Society for Research in Child Development) A Canadian study looked at monolingual and bilingual six year-olds on three verbal tasks and one nonverbal task of executive control. The study found that different factors were responsible for the language- and non-language-related outcomes of bilingualism than found in previous research. This study is also unique in that it controlled for other factors that are often associated with bilingualism, including differences in culture, socioeconomic status, immigration history, and language. -
Europe goes for computing technologies as driver for competitiveness
7 Feb 2012 | 9:00 pm(European Network of Excellence on High Performance and Embedded Architecture and Compilation) The HiPEAC 2012 Conference, supported by the European Commission, brings together 500 computing systems stakeholders from all over the world. HiPEAC 2012 is the first computing conference to implement a journal-first publication model, resulting in 50 percent more submissions and three times more delegates.
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YouTube Videos
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Rep. John Kline on Obama's Education Proposals
8 Feb 2012 | 4:09 pmRep. John Kline on Obama's Education Proposals www.washingtontimes.com Rep. John Kline, R-Minn., Chairman of the House Committee on Education and the Workforce, comments on various proposals by President Obama to control the cost of higher education during an exclusive interview with the Washington Times. From: washingtontimes Views: 0 0 ratings Time: 04:07 More in News & Politics -
euronews learning world - Education moves
3 Feb 2012 | 10:50 ameuronews learning world - Education moves www.euronews.net In this edition of Learning World we look at getting to and from school. In theory, the school run should be affordable and safe but in poor and isolated areas, difficulties getting to school can lead to children to not go. *Vietnam: Cycling to school* In Da Nang, in Vietnam, many families are very poor. Even a simple thing like the school run can pose a huge problem here. But for one boy, life is easier now that he has a bicycle to ride to school. Duc's mother says she's happy that both her children can now go to school. -
Chromebooks for Education
21 Sep 2011 | 6:41 pmChromebooks for Education For more information, visit: google.com/chromebook/education From: googlechrome Views: 263649 605 ratings Time: 02:13 More in People & Blogs -
Education
14 Sep 2011 | 3:06 pmEducation Video that you must watch: www.youtube.com What shall I video blog about tomorrow!? Go vote!: bit.ly Add me on facebook: facebook.com Email me: danbrownuniverse@gmail.com Second Channel: youtube.com From: pogobat Views: 29413 1261 ratings Time: 05:38 More in Education -
Education for Uncertain Futures
11 Jul 2011 | 2:22 amEducation for Uncertain Futures As young people face an ever more uncertain climate beyond education join our panel as they ask; can our educators afford not to become more radically futures-aware? Listen to the full audio file: www.thersa.org From: theRSAorg Views: 8271 133 ratings Time: 23:48 More in Nonprofits & Activism
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tweenteacher.com
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New Edutopia Post: 7 Tips for Digital Learners
2 Feb 2012 | 5:02 amMy latest post on Edutopia just went live. “7 Tips for Digital Learners” picks apart some of the skills that students of any age should have in order to succeed online. Of course, that’s not to say that there aren’t steps that teachers can take to encourage the development of these tips, but that’s for another post! Anyway, it’s important for learners to know what they’re in for when starting down the road of digital learning. Talk to you all soon! I’m prepping a new post on ELD strategies so heads up, it’s on its way! -Heather… -
Teaching Beyond the Bell
18 Jan 2012 | 7:40 pmIn celebration of The California Writing Project and Digital Learning Day, I was asked to write a post on some of what I’m doing with technology in the classroom. So I decided to write about what I’m actually doing outside of the classroom…in a virtual classroom that is. You can read the post, “Using Technology to Model Lifelong Learning Beyond the Bell,” here. I am always happy to lend my voice and words to support the Writing Project. Don’t know what I”m talking about? Looking for the best, life and practice-changing professional development… -
Tweenteacher Class on Project Based Writing
9 Jan 2012 | 7:18 pmHey all, Guess what? I’m going to be facilitating a class for Sheryl Nussbaum-Beach’s Powerful Learning Practice. The six-week course is on Project Based Writing, a strategic way to bring in authentic assessments and meaningful learning into any Language Arts program, elementary through secondary. If you know anything about my teaching style, it’s about reciprocal learning, engaging instruction, and breaking down the walls between school life and real life. But it’s always easier to jump start into a new unit if someone has tried strategies out already, which is… -
Edutopia Post: Trying Something New in Your Classroom for 30 Days
19 Dec 2011 | 8:12 pmI’ve just recently posted a new article on my Edutopia blog, one that challenges teachers to try something new in their classroom for 30 days. As many of my readers know, my students are currently working on their Advocacy/Memoir speeches that mimic those presented at TED. In a recent assignment, I asked my students to analyze a particular speech where the speaker took on the task of trying something new for 30 days. He challenges the audience to see the value in the adoption regardless of whether the new task is made into a habit or not. In my Edutopia post, I challenge teachers to do… -
A Tribute to Tony, our School Counselor
15 Dec 2011 | 3:08 pmAt times, I find myself in awe of some of the dedicated and self-sacrificing individuals that have devoted themselves to our students. These are the diamonds, the people who live this work, who breathe it, who take home the lost battles and get up everyday to battle again. One such person is our school counselor, Tony Phuong. Tony has been at my school for a while and no matter the cohort of students under his guidance, he serves them with the same support, kindness, tough-love, and wisdom year after year. He meets the most challenging students with a smile before making them push themselves…
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New Scientist - Online News
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Lost treasures: The Loch Ness monster that got away
9 Feb 2012 | 4:00 amIn the 1600s, the specimen of a curious long-necked seal emerged. It could explain tall stories of sea serpents – if only it hadn't been mislaid -
Instant Expert: Sleep
9 Feb 2012 | 3:46 amIn our latest expert guide, Derk-Jan Dijk and Raphaëlle Winsky-Sommerer explore the mystery of sleep and what modern life is doing to it -
Shark-eating shark snapped in Australia
8 Feb 2012 | 10:11 amA tasselled wobbegong shark has been photographed eating another shark for the first time -
Nerve probe controls cyborg moth in flight
8 Feb 2012 | 10:00 amHalf-moth, half machine, a new generation of remote-controlled insects could one day be used as spies -
Today on New Scientist: 8 February 2012
8 Feb 2012 | 10:00 amAll today's stories on newscientist.com, including: US bat killer strikes in Europe and anonymous leaks emails from Syrian President's office
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LiveScience.com
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Where Did I Park? Brain Treatment May Enhance Spatial Memory
8 Feb 2012 | 4:29 pmSending electrical pulses into the brain may improve memory. -
1 in 10 Doctors Admit Lying in the Past Year
8 Feb 2012 | 4:24 pmAbout 1 in 10 physicians say they have told patients something that was not true in the last year. -
Bacterial 'Glue' is One of Nature's Stickiest Substances
8 Feb 2012 | 3:12 pmThe tiny water bacterium Caulobacter crescentus secretes a sugary substance so sticky that just a tiny bit could hold several cars together. -
Teen Pregnancy Rate Hits 40-Year Low
8 Feb 2012 | 1:16 pmTeenage pregnancy, birth and abortion rates have steadily decreased over the last two decades. -
Is It Possible to Reanimate the Dead?
8 Feb 2012 | 1:07 pmFrankenstein's monster is probably not a possibility, but scientists are getting better at bringing people back to life.
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Wired: Wired Science
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Black Hole Eats Asteroids, Burps Out X-Rays
8 Feb 2012 | 2:31 pmThe supermassive black hole at the center of our galaxy may be constantly snacking on asteroids. A new study finds that asteroids at least 12 miles wide falling into the black hole would account for the regular bright x-ray flares seen through telescopes. Though nothing, including light, can escape a black hole, most are ringed by a disk of gas and dust. As it falls in, this material heats up to incredible temperatures, generating energy. For several years, NASA’s Chandra X-ray Observatory has spotted daily fluctuations in the emissions coming from the Milky Way’s central black… -
European Cave Spiders Produce Super-Stretchy Silk
8 Feb 2012 | 2:00 pmScientists have discovered some of the most stretchable spider silk ever, which can elongate up to 7.5 times its initial length. European cave spiders produce the silk to build egg sacs that protect their developing young. Spider silk is a remarkable material known for its strength and toughness. Most species secrete seven or eight types of silk for different purposes. Dragline silk, for instance, anchors spiders to a surface and is used as the backbone of most webs while other silks are used for web scaffolding or to wrap captured prey. Female European cave spiders (Meta menardi), which live… -
Asia and Americas on Course for Arctic Collision
8 Feb 2012 | 1:06 pmIt’ll be a geological showdown for the ages, with North America, South America, Europe and Asia colliding head-on over the North Pole to create a supercontinent called Amasia. Unfortunately, nobody we know will be around to watch the collision, which won’t happen for another 50 million years or more. But it’s still fun to imagine. “The snapshot that is the present is smack-dab in the middle of what we call the supercontinent cycles,” said geologist Ross Mitchell of Yale University, lead author of a Feb. 8 Nature prediction of supercontinental trajectories. -
The Unusual Physics of Floating Pyramids
8 Feb 2012 | 11:00 amBy Kate McAlpine, ScienceNOW Think floating pyramids are more metaphysics than physics? Think again. Results just in from an experiment that levitated open-bottomed paper pyramids on gusts of air reveal a curious phenomenon: When it comes to drifting through the air, top-heavy designs are more stable than bottom-heavy ones. The finding may lead to robots that fly not like insects or birds but like jellyfish. Physicist Jun Zhang and his colleagues at New York University wanted to better understand how flying bugs control the orientations of their bodies. Do they have to work at it, or are they… -
Tiny Tarsiers Talk in High-Pitched Code
8 Feb 2012 | 7:04 amBy Mark Brown, Wired UK The Philippine tarsier is a tiny primate with a seriously high voice. The saucer-eyed mammal can let out (and listen to) squeaks and squeals at such a high frequency that it effectively gives the mammal a private communication channel. A team of researchers, led by Marissa Ramsier of Humboldt State University in California, found that the tiny tarsier can hear and emit sounds in the ultrasound range — that’s above 20 kHz. Most humans can’t hear in that range, and a dog whistle is pitched to be just inside ultrasound, somewhere between 22 and 23 kHz. A…
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Science
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Drilling Team Finally Hits Antarctica's Liquid Lake
9 Feb 2012 | 12:00 amAfter years of trying, Russian scientists say they have drilled into an Antarctic lake that is buried beneath more than two miles of ice. They are looking for signs of life that haven't been exposed to sky in 20 million years.» E-Mail This » Add to Del.icio.us -
A New Weapon Against Nukes: Social Media
8 Feb 2012 | 2:38 pmA top State Department official wants to unleash the power of Twitter, Facebook and other services to crowdsource the fight to control the world's nuclear weapons.» E-Mail This » Add to Del.icio.us -
'Amasia': The Next Supercontinent?
8 Feb 2012 | 2:02 pmMore than 100 million years from now, the Americas and Asia might fuse together, squishing the Arctic Ocean shut in the process. That's according to a new model that predicts where the next supercontinent may form. But don't worry: Humans will likely be long gone by then.» E-Mail This » Add to Del.icio.us -
'Rasputin Was My Neighbor' And Other True Tales Of Time Travel
8 Feb 2012 | 6:44 amThere are people who live long enough to create a link — a one-generation link — to figures from what feels like a distant past. And their presence among us shrinks history.» E-Mail This » Add to Del.icio.us -
Robots Encountering Socks
6 Feb 2012 | 7:55 amSuppose you're a robot. If you had a camera in your head, and you could watch a human doing a simple task, like bunching a pair of socks, could you, just by watching, learn to do it too?» E-Mail This » Add to Del.icio.us
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ScienceBlogs : Combined Feed
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Links for 2011-02-09 [Uncertain Principles]
9 Feb 2012 | 4:24 amWhy The Planet Doesn't Care About Your Eco-Friendly Lifestyle | Co.Exist: World changing ideas and innovation Co.Exist:What does the average environmentalist get wrong? Wagner: Environmentalists, all too often, think that the best way to go about solving the problem is to get everyone to do as they--we, I included--do. I don't eat meat. I don't drive. But individual do-gooderism won't solve global warming. And it may actually be counter-productive, for two reasons. First, there's a well-documented psychological phenomenon called "single-action bias." You do one thing, and you move on. You… -
Why did Phobos-Grunt fail? [Greg Laden's Blog]
9 Feb 2012 | 2:40 amThe Russian probe destine for the Mars system never made it out of Earth Orbit and recently crashed back into Planet Earth. Why did the rocket ship fail? There has apparently been a lot of obfuscation of what caused this disaster, but now there is some better information. It may have been caused by a computer programming error. From Irene Klotz at Discovery News: In a report to be presented to Russian Deputy Prime Minister Dmitry Rogozin on Tuesday, investigators concluded that the primary cause of the failure was "a programming error which led to a simultaneous reboot of two working channels… -
Yes, Virginia, there is an antivaccine movement (efforts to deny it notwithstanding) [Respectful Insolence]
9 Feb 2012 | 12:00 amThere are times when I want to fall down on my knees and give thanks for certain cranks. I mean, where would my blogging material come from, were it not for antivaccine loons, quacks, cranks, creationists, and animal rights terrorists providing me with an unending stream of blog fodder? Were they all to disappear, I'd be reduced to blogging about puppies or music or something, and, trust me, you wouldn't want that. Of course, my readership would flee me faster than a advocates of gay marriage flee the Republican Party; so I guess it wouldn't matter. I know which side my bread is buttered on;… -
The Big Bang for Beginners [Starts With A Bang]
8 Feb 2012 | 11:07 pm"It took less than an hour to make the atoms, a few hundred million years to make the stars and planets, but five billion years to make man!" -George Gamow Let's pretend that, for all of our history on Earth, we had never once bothered to look up with any instruments beyond what our own eyes could offer. Imagine that all the technology we'd have would be the same -- telescopes, electronics, GPS, etc. -- as would our fundamental scientific knowledge -- Einstein's General Relativity, the Standard Model of Particle Physics, etc. -- but we had just never bothered to turn our attentions toward the… -
I have never seen a purple squirrel... [Dynamics of Cats]
8 Feb 2012 | 9:59 pmbut now I hope to see one: Read the rest of this post... | Read the comments on this post... Also check out the featured ScienceBlog of the week: Inside the Outbreaks on the ScienceBlogs Book Club
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ScienceAlert - Latest Stories
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Simple names win more favours
8 Feb 2012 | 6:00 amPeople with simple and easy-to-pronounce names are more likely to win friends and favours, a new study shows. -
Bionic eye trials ready in 2013
8 Feb 2012 | 6:00 amA bionic eye implant that stimulates the brain’s vision centre will be ready for human trials in 2013, vision researchers say. -
Climate raises risk of dengue
8 Feb 2012 | 6:00 amFuture changes in temperature and rainfall can increase the risk of dengue fever in northern Western Australia, a researcher says. -
‘Dire future’ awaits big trees
8 Feb 2012 | 6:00 amThe world’s “biggest and most magnificent” trees are threatened by habitat fragmentation, loggers and more, a leading scientist says. -
Smoking dads: leukemic kids
8 Feb 2012 | 6:00 amChildren whose fathers smoke heavily during conception have a 35% higher risk of developing cancer, new research shows.
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Comics Worth Reading
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Princess #4: Mea Culpa
8 Feb 2012 | 5:17 amI owe the guys behind Princeless an apology. It’s a good read, a fresh take and an entertaining story, the kind of wonderfully surprising discovery it’s a joy to find among independent small-press comics. After previewing the first issue, I reviewed issue #2 and issue #3, and I was critical of the series based on what I had hoped to see, not what it was. I had certain expectations, based on how the title was presented to me, and those weren’t met, but it wasn’t fair of me to be as harsh as I was. A new comic has a huge uphill battle, and I want to be clear that this is… -
Next Amelia Rules! Book to Be the Last
7 Feb 2012 | 5:52 pmIn this lengthy interview with Jimmy Gownley at PublishersWeekly.com, the author looks back at the history of his series Amelia Rules! From being self-published to being picked up by Simon & Schuster in 2008, his series has been running for over 10 years. It’s a wonderful overview of what used to be possible in the comic market, how much things have changed over the years, and how Gownley has adapted to the changing industry. The most recent Amelia Rules!, The Meaning of Life… and Other Stuff, was one of my Best Graphic Novels of 2011. However, in the article, he also reveals… -
Manga Out Loud Looks at Fan Behavior and Bakuman
7 Feb 2012 | 5:17 pmIn the latest Manga Out Loud podcast, * Ed and I talk about Bakuman * Erica briefly discusses the MangaNEXT convention * and then Erica Friedman, Ed, and I discuss the questions of fan entitlement, education, and the future of companies in the industry. We’re hoping for plenty of feedback, here, at MangaOutLoud.com, or on Twitter. Similar Posts: Bakuman Manga Out Loud Podcast: Ed and I Discuss the Manga § Manga Out Loud Podcast Tackles Peepo Choo § Manga Out Loud Tackles Digital Manga § Wandering Son on Manga Out Loud § Manga Out Loud: My First Podcast -
I’m Part of Love and Capes Now!
7 Feb 2012 | 1:38 pmThom Zahler offered a chance to buy his MegaCon Orlando print and get drawn in line with Mark and Abby, so that’s me and KC there on the left. (In green and purple. Together, we’re a supervillain.) I’m thrilled to be part of the Love & Capes universe, since it’s one of my favorite comics going right now, never failing to make me smile. And since KC and I spent our tenth anniversary at the park that shall not be named, I couldn’t pass up a combination of both those fun things. A new Love & Capes miniseries starts later this year, in case you wanted a… -
Genshiken Sequel Series Coming to US This Fall
7 Feb 2012 | 1:23 pmGenshiken Book 2 ANN is reporting that Kodansha will release the first book of Genshiken: Second Season in the U.S. on September 4. (There have been two volumes out so far in Japan.) It took me a couple of tries to appreciate the fan-favorite series, about an anime/manga/cosplay/videogame club, before I got the appeal, but once you know the characters, it’s a lot of fun. The first series ran nine volumes (published by Del Rey), ending with graduation. To prepare for the sequel, Kodansha will also release an omnibus volume of the first three books on May 22. Similar Posts:…
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PDX Comic Geek
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Comic Review: Rachel Rising #5
9 Feb 2012 | 2:10 amRachel Rising #5 My only complaint, the only possible complaint I can think of with this book is that it’s too short. Take a simple premise, that of a girl rising from the dead after a traumatic event, and then let the thing unfold as though it were normal. There are no special explanations here beyond what you could expect, nothing fancy, just a story of a girl who should be dead but isn’t. The entire thing has a really creepy feel, through the obvious disturbance but also the normality that people strike forwards with. It’s that overall calmness that drives forward the… -
Comic Review: X-Club #3, “We do Science”.
8 Feb 2012 | 4:11 amX-Club #3 Marvel, I am disappoint. You had me at the start of this issue of X-Club. Sure the first two were kinda passe, with the set up and the drone of science, but by the end of issue two, you really had something going there, especially with Doctor Nemesis and his telepathic starfish. And at the start of this issue it was humming along nicely, great with the laughs and the drama. But then you went and ruined it with two old, Old, OLD story devices. The X-Club, scientists of an X-Men variety, have set up an orbital elevator as some good PR, but it’s all gone horribly wrong… -
Comic Review: Uncanny X-Force #21, “Otherworld Chapter Two”.
7 Feb 2012 | 1:15 amUncanny X-Force #21 This story is brutal, but that could be due just to my sensibilities. Fantomex is one of my favorite characters and to watch what happens to him in this book is truly troubling. Remember last issue? Fantomex was ruled guilty of killing the child Apocalypse and as such was sentenced to death in Otherworld. But death isn’t just permanent, it’s retroactive – he is to be expunged from all realities and times, a thing that never was nor shall be remembered. Psylocke, in her Britain garb rescues him but knows the poison leaks through his veins,… -
Comic Review: Uncanny X-Men #6
5 Feb 2012 | 11:15 pmUncanny X-Men #6 There is a kind of fiction I really enjoy, regardless of whether it’s fantasy or sci-fi, it involves the setting of a believable and thorough history. I’m the kind of person who reads through all the quests in the games so that I understand why I’m doing certain things, rather than just following blindly. This issue of Uncanny was really something, because it established that history and then allowed the story to unfold within it. With the talk of factions and gods, false gods and time, it’s a thorough read, though you need to set time aside to… -
Comic Preview: Soulfire #7
5 Feb 2012 | 2:52 amSoulfire #7 So Soulfire, the book about fairies in the real world, is taking a detour from that same real world, the one that makes it grounded and interesting, and has left that behind for a mystical fantasy land where things are really bad, apparently. But with that mystical fantasy land we’ve lost our connection to the story and as such my interest is gone. That’s the review if you want, the next two paragraphs are me explaining my decision. Certainly the art is sumptuous, fairies tend to wear very little and look good doing it, but the machinations of the story have taken…
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PLoS Biology: New Articles
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Development and Function of Invariant Natural Killer T Cells Producing TH2- and TH17-Cytokines
7 Feb 2012 | 2:00 pmby Hiroshi Watarai, Etsuko Sekine-Kondo, Tomokuni Shigeura, Yasutaka Motomura, Takuwa Yasuda, Rumi Satoh, Hisahiro Yoshida, Masato Kubo, Hiroshi Kawamoto, Haruhiko Koseki, Masaru Taniguchi There is heterogeneity in invariant natural killer T (iNKT) cells based on the expression of CD4 and the IL-17 receptor B (IL-17RB), a receptor for IL-25 which is a key factor in TH2 immunity. However, the development pathway and precise function of these iNKT cell subtypes remain unknown. IL-17RB iNKT cells are present in the thymic CD44 NK1.1 population and develop normally even in the absence of IL-15,… -
Genome-Wide Analysis of the World's Sheep Breeds Reveals High Levels of Historic Mixture and Strong Recent Selection
7 Feb 2012 | 2:00 pmby James W. Kijas, Johannes A. Lenstra, Ben Hayes, Simon Boitard, Laercio R. Porto Neto, Magali San Cristobal, Bertrand Servin, Russell McCulloch, Vicki Whan, Kimberly Gietzen, Samuel Paiva, William Barendse, Elena Ciani, Herman Raadsma, John McEwan, Brian Dalrymple, other members of the International Sheep Genomics Consortium Through their domestication and subsequent selection, sheep have been adapted to thrive in a diverse range of environments. To characterise the genetic consequence of both domestication and selection, we genotyped 49,034 SNP in 2,819 animals from a diverse collection of… -
Multi-Cellular Rosettes in the Mouse Visceral Endoderm Facilitate the Ordered Migration of Anterior Visceral Endoderm Cells
7 Feb 2012 | 2:00 pmby Georgios Trichas, Aaron M. Smith, Natalia White, Vivienne Wilkins, Tomoko Watanabe, Abigail Moore, Bradley Joyce, Jacintha Sugnaseelan, Tristan A. Rodriguez, David Kay, Ruth E. Baker, Philip K. Maini, Shankar Srinivas The visceral endoderm (VE) is a simple epithelium that forms the outer layer of the egg-cylinder stage mouse embryo. The anterior visceral endoderm (AVE), a specialised subset of VE cells, is responsible for specifying anterior pattern. AVE cells show a stereotypic migratory behaviour within the VE, which is responsible for correctly orientating the anterior-posterior axis. -
Reconstructing Speech from Human Auditory Cortex
31 Jan 2012 | 2:00 pmby Brian N. Pasley, Stephen V. David, Nima Mesgarani, Adeen Flinker, Shihab A. Shamma, Nathan E. Crone, Robert T. Knight, Edward F. Chang How the human auditory system extracts perceptually relevant acoustic features of speech is unknown. To address this question, we used intracranial recordings from nonprimary auditory cortex in the human superior temporal gyrus to determine what acoustic information in speech sounds can be reconstructed from population neural activity. We found that slow and intermediate temporal fluctuations, such as those corresponding to syllable rate, were accurately… -
Desperately Seeking Stable 50-Year-Old Landscapes with Patches and Long, Wide Corridors
31 Jan 2012 | 2:00 pmby Paul Beier, Andrew J. Gregory
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PLoS ONE Alerts: New Articles
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Cells Assemble Invadopodia-Like Structures and Invade into Matrigel in a Matrix Metalloprotease Dependent Manner in the Circular Invasion Assay
8 Feb 2012 | 2:00 pmby Xinzi Yu, Laura M. Machesky The ability of tumor cells to invade is one of the hallmarks of the metastatic phenotype. To elucidate the mechanisms by which tumor cells acquire an invasive phenotype, in vitro assays have been developed that mimic the process of cancer cell invasion through basement membrane or in the stroma. We have extended the characterization of the circular invasion assay and found that it provides a simple and amenable system to study cell invasion in matrix in an environment that closely mimics 3D invasion. Furthermore, it allows detailed microscopic analysis of both… -
Rapid Insulinotropic Action of Low Doses of Bisphenol-A on Mouse and Human Islets of Langerhans: Role of Estrogen Receptor β
8 Feb 2012 | 2:00 pmby Sergi Soriano, Paloma Alonso-Magdalena, Marta García-Arévalo, Anna Novials, Sarheed J. Muhammed, Albert Salehi, Jan-Ake Gustafsson, Ivan Quesada, Angel Nadal Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical (EDC) used as the base compound in the manufacture of polycarbonate plastics. It alters pancreatic β-cell function and can be considered a risk factor for type 2 diabetes in rodents. Here we used ERβ−/− mice to study whether ERβ is involved in the rapid regulation of KATP channel activity, calcium signals and insulin release elicited by environmentally relevant… -
Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization
8 Feb 2012 | 2:00 pmby Lukas Baitsch, Amandine Legat, Leticia Barba, Silvia A. Fuertes Marraco, Jean-Paul Rivals, Petra Baumgaertner, Céline Christiansen-Jucht, Hanifa Bouzourene, Donata Rimoldi, Hanspeter Pircher, Nathalie Rufer, Maurice Matter, Olivier Michielin, Daniel E. Speiser Inhibitory receptors mediate CD8 T-cell hyporesponsiveness against cancer and infectious diseases. PD-1 and CTLA-4 have been extensively studied, and blocking antibodies have already shown clinical benefit for cancer patients. Only little is known on extended co-expression of inhibitory receptors and their ligands. Here we analyzed… -
CTCF Mediates the Cell-Type Specific Spatial Organization of the Kcnq5 Locus and the Local Gene Regulation
8 Feb 2012 | 2:00 pmby Licheng Ren, Yang Wang, Minglei Shi, Xiaoning Wang, Zhong Yang, Zhihu Zhao Chromatin loops play important roles in the dynamic spatial organization of genes in the nucleus. Growing evidence has revealed that the multivalent functional zinc finger protein CCCTC-binding factor (CTCF) is a master regulator of genome spatial organization, and mediates the ubiquitous chromatin loops within the genome. Using circular chromosome conformation capture (4C) methodology, we discovered that CTCF may be a master organizer in mediating the spatial organization of the kcnq5 gene locus. We characterized… -
Global Effects of Catecholamines on Actinobacillus pleuropneumoniae Gene Expression
8 Feb 2012 | 2:00 pmby Lu Li, Zhuofei Xu, Yang Zhou, Lili Sun, Ziduo Liu, Huanchun Chen, Rui Zhou Bacteria can use mammalian hormones to modulate pathogenic processes that play essential roles in disease development. Actinobacillus pleuropneumoniae is an important porcine respiratory pathogen causing great economic losses in the pig industry globally. Stress is known to contribute to the outcome of A. pleuropneumoniae infection. To test whether A. pleuropneumoniae could respond to stress hormone catecholamines, gene expression profiles after epinephrine (Epi) and norepinephrine (NE) treatment were compared with…
